Kamagra Oral Jelly Online - Analogs and Substitutes
Among the regulators of male potency the most popular is Viagra. But its main drawback is the high cost due to the incredible popularity. You can buy Kamagra online, which costs less than the well-known blue pills, but contains a similar active ingredient.
Main active ingredient
The drug Kamagra is manufactured by Centurion Laboratories and contains in its composition the active ingredient sildenafil. Viagra has similar composition. Sildenafil refers to phosphodiesterase-5 (PDE-5) inhibitors. The Kamagra is available in a form of a pill or jelly. Tablets contain 100 mg of the active substance, 4 pcs. in the package under the name "KAMAGRA-100 GOLD". Packaging "KAMAGRA ORAL JELLY" contains 7 sachets of jelly, each with 100 mg of sildenafil. The jelly form allows the drug to enter the bloodstream and begin to act in a matter of minutes.
Principle of action
The basis of the action of sildenafil is the suppression of the activity of the enzyme phosphodiesterase-5. This enzyme destroys cGMP involved in the development of erection. The drug increases the flow to the penis and contributes to the normal course of sexual arousal. With sexual arousal, the cells of the inner lining of the vessels in the penis start producing nitric oxide (NO). This substance stimulates the synthesis of guanylate cyclase and increases the concentration of cGMP. It causes relaxation of the vascular smooth muscle of the cavernous bodies in penis. As a result, the arteries are dilates, the blood flow increases, and it fills the cavernous bodies, as a result an erection appears. In the human body there are 11 types of PDE. Different forms of this enzyme are located in the myocardium, retina, skeletal muscles, and the walls of various vessels. Since Kamagra affects on all types of phosphodiesterase to some extent, this may lead to the development of some undesirable effects. Sildenafil is 10 times more strongly associates with PDE-5 than with PDE-6, 80 times stronger than PDE-1. With other subtypes of this enzyme, its affinity is 1000, 4000 times or more.
Kamagra is indicated in the next cases:
Kamagra should not be used in the next cases:
The most frequently occurring side effects after the use of Kamagra (more than 2% of men) are:
Instructions for use
If you already found where to buy cheap Kamagra (online or in pharmacy chains), then before using it, read the rules for taking the medicine.
The treatment for enhancing the erection in the form of tablets should be taken 2-3 hours before the intended sexual intercourse, regardless of the meal. The drug is taken orally, not chewed and washed down with a moderate amount of water.
The jelly dosage form is poured from the bag into the oral cavity and absorbed. It should be drunk 20-30 minutes before sex.
Do not take more than 100 mg of Kamagra per day. Otherwise, increases the risk of undesirable effects.
Interaction with other drugs
While simultaneous use with nitrates increases the risk of a sharp uncontrolled drop in blood pressure levels.
The simultaneous usage of sildenafil with drugs that inhibit cytochrome P450, increases the concentration of the drug to enhance erection and slows down its elimination from the body, which contributes to the development of side effects. These drugs include:
Analogs and Substitutes
Generic Kamagra is much more available and cheaper than the popular blue pills. But if the developed effect does not satisfies you or undesirable reactions aroses, then you can try using other drugs to enhance erection with a similar mechanism of action.
Medication with sildenafil in the composition
Sildenafil is an active substance in Kamagra. Instead of this drug, you can try any other with a similar composition: Viagra, Maxigra, Sildenafil, Dynamic, Vizarsin, Vivaira, etc.